Article
The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice.
Immunity - 1 Jul 1996
Sytwu H K, Liblau R S, McDevitt H O
Abstract excerpt
The possible involvement of Fas/APO-1 (CD95) and TNF in antigen-specific AICD of thymocytes and mature T cells has been investigated. Antigenic stimulation in vivo of influenza hemagglutinin (HA)-specific TCRtg mice was used to demonstrate that the kinetics of thymocyte and peripheral CD4+ T cell...
Topics
- Amino Acid Sequence
- Animals
- Apoptosis
- Base Sequence
- Clonal Deletion
- Crosses, Genetic
- Dose-Response Relationship, Immunologic
- Hemagglutinins, Viral
- Immunophenotyping
- Influenza A virus
- Lymphocyte Activation
- Lymphoproliferative Disorders
