Article
Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells.
European journal of immunology - 1 Sept 1993
Russell J H, Wang R
Abstract excerpt
Antigen receptor-directed suicide plays an important role in the elimination of potentially autoaggressive immature T cells during thymic differentiation. Here we demonstrated evidence for a second pathway of receptor-directed suicide in mature T cells that is missing in a mutant strain (gld) of...
Topics
- Animals
- Antigen-Presenting Cells
- Apoptosis
- Autoimmune Diseases
- Female
- Lymphocyte Activation
- Lymphoproliferative Disorders
- Male
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mutation
