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Article

Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells.

European journal of immunology - 1 Sept 1993

Russell J H, Wang R

Abstract excerpt

Antigen receptor-directed suicide plays an important role in the elimination of potentially autoaggressive immature T cells during thymic differentiation. Here we demonstrated evidence for a second pathway of receptor-directed suicide in mature T cells that is missing in a mutant strain (gld) of mice with an "autoimmune" lymphoproliferative syndrome. The defect is evident within the gld activated T cell and does...

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Source

Identifiers

PMID: 8370416
DOI: 10.1002/eji.1830230951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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