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Article

Characterization of echinocandin-resistant mutants of Candida albicans: genetic, biochemical, and virulence studies.

Infection and immunity - 1 Aug 1996

Kurtz M B, Abruzzo G, Flattery A, Bartizal K, Marrinan J A, Li W, Milligan J, Nollstadt K, Douglas C M

Abstract excerpt

The pneumocandins are potent antifungal agents of the echinocandin class which are under development for use as broad-spectrum antimycotic therapy. One important consideration for any new therapeutic class for treating serious fungal infections is the potential for drug resistance development. In this study we have isolated and characterized four independent spontaneous Candida albicans mutants resistant to the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 8757860
DOI: 10.1128/iai.64.8.3244-3251.1996
PMCID: PMC174214

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Source receipt: pubmed, retrieved 7 Sept 2026.

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