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Article

Ku86-Deficient Mice Exhibit Severe Combined Immunodeficiency and Defective Processing of V(D)J Recombination Intermediates

1 Aug 1996

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8756720
DOI: 10.1016/s0092-8674(00)80111-7

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Ku86-Deficient Mice Exhibit Severe Combined Immunodeficiency and Defective Processing of V(D)J Recombination IntermediatesPMID 8756720Read ↗

A Human Severe Combined Immunodeficiency (SCID) Condition with Increased Sensitivity to Ionizing Radiations and Impaired V(D)J Rearrangements Defines a New DNA Recombination/Repair DeficiencySemantic proximity Read ↗

Leaky Scid Phenotype Associated with Defective V(D)J Coding End Processing in Artemis-Deficient MiceSemantic proximity Read ↗

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Deletion of Ku86 causes early onset of senescence in mice.Semantic proximity Read ↗

Activation of V(D)J recombination induces the formation of interlocus joints and hybrid joints in scid pre-B-cell lines.Semantic proximity Read ↗

Regulation of V(D)J recombination.Semantic proximity Read ↗

Mutational analysis of all conserved basic amino acids in RAG-1 reveals catalytic, step arrest, and joining-deficient mutants in the V(D)J recombinase.Semantic proximity Read ↗

Defective nonhomologous end joining blocks B-cell development in FLT3/ITD mice.Semantic proximity Read ↗

The Candida albicans Ku70 modulates telomere length and structure by regulating both telomerase and recombination.Semantic proximity Read ↗

Temporally uncoupled signal and coding joint formation in human V(D)J recombination.Semantic proximity Read ↗

Restrictions limiting the generation of DNA double strand breaks during chromosomal V(D)J recombination.Semantic proximity Read ↗

DNA-PKcs chemical inhibition versus genetic mutation: Impact on the junctional repair steps of V(D)J recombination.Semantic proximity Read ↗

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