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Article

Leaky Scid Phenotype Associated with Defective V(D)J Coding End Processing in Artemis-Deficient Mice

1 Dec 2002

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 12504013
DOI: 10.1016/s1097-2765(02)00755-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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Leaky Scid Phenotype Associated with Defective V(D)J Coding End Processing in Artemis-Deficient MicePMID 12504013Read ↗

Novel spontaneous deletion of artemis exons 10 and 11 in mice leads to T- and B-cell deficiency.Semantic proximity Read ↗

Impact of a hypomorphic Artemis disease allele on lymphocyte development, DNA end processing, and genome stability.Semantic proximity Read ↗

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Artemis, a novel guardian of the genome.Semantic proximity Read ↗

Dclre1c-Mutation-Induced Immunocompromised Mice Are a Novel Model for Human Xenograft Research.Semantic proximity Read ↗

A Novel Non-Coding Variant in DCLRE1C Results in Deregulated Splicing and Induces SCID Through the Generation of a Truncated ARTEMIS Protein That Fails to Support V(D)J Recombination and DNA Damage Repair.Semantic proximity Read ↗

Lentivirus Mediated Correction of Artemis-Deficient Severe Combined ImmunodeficiencySemantic proximity Read ↗

A non-leaky Artemis-deficient mouse that accurately models the human severe combined immune deficiency phenotype, including resistance to hematopoietic stem cell transplantation.Semantic proximity Read ↗

Defective Artemis nuclease is characterized by coding joints with microhomology in long palindromic‐nucleotide stretchesSemantic proximity Read ↗

Partial T and B lymphocyte immunodeficiency and predisposition to lymphoma in patients with hypomorphic mutations in Artemis.Semantic proximity Read ↗

Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcsSemantic proximity Read ↗

Clinical and Genetic Characterization of Patients with Artemis Deficiency in Japan.Semantic proximity Read ↗

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