Article
Semidominant mutations in the yeast Rad51 protein and their relationships with the Srs2 helicase.
Molecular and cellular biology - 1 Sept 1996
Chanet R, Heude M, Adjiri A, Maloisel L, Fabre F
Abstract excerpt
Suppressors of the methyl methanesulfonate sensitivity of Saccharomyces cerevisiae diploids lacking the Srs2 helicase turned out to contain semidominant mutations in Rad5l, a homolog of the bacterial RecA protein. The nature of these mutations was determined by direct sequencing. The 26 mutations characterized were single base substitutions leading to amino acid replacements at 18 different sites. The great...
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