Article
Combined analysis of inherited polymorphisms in arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1, microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk.
Cancer research - 1 Sept 1996
Brockmöller J, Cascorbi I, Kerb R, Roots I
Abstract excerpt
Foreign compound-metabolizing enzymes may modify the risk of chemically induced cancer. We wanted to examine enzymes with putative relevance in urinary bladder cancer using molecular genetic analyses of heritably polymorphic enzymes. Arylamine N-acetyltransferase (NAT2); glutathione S-transferase...
Topics
- Aged
- Alleles
- Arylamine N-Acetyltransferase
- Base Sequence
- Cytochrome P-450 Enzyme System
- Epoxide Hydrolases
- Female
- Glutathione Transferase
- Humans
- Isoenzymes
- Male
- Microsomes
- Middle Aged
- Molecular Sequence Data
- Polymorphism, Genetic
- Risk Factors
- Urinary Bladder Neoplasms