Article
Polymorphic enzymes, urinary bladder cancer risk, and structural change in the local industry.
Journal of toxicology and environmental health. Part A - 1 Jan 2012
Ovsiannikov Daniel, Selinski Silvia, Lehmann Marie-Louise, Blaszkewicz Meinolf, Moormann Oliver, Haenel Matthias W, Hengstler Jan G, Golka Klaus
Abstract excerpt
In the 1990s, an uncommonly high percentage of glutathione S-transferase M1 (GSTM1) negative bladder cancer cases (70%) was reported in the greater Dortmund area. The question arose as to whether this uncommonly high percentage of GSTM1 negative bladder cancer cases was due to environmental and/or occupational exposure decades ago. Thus, 15 years later, another study on bladder cancer was performed in the same...
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