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Article

Cytochrome P4501A2 phenotype and bladder cancer risk: The Shanghai bladder cancer study.

International journal of cancer - 1 Mar 2012

Tao Li, Xiang Yong-Bing, Chan Kenneth K, Wang Renwei, Gao Yu-Tang, Yu Mimi C, Yuan Jian-Min

Abstract excerpt

Cytochrome P450 1A2 (CYP1A2) is hypothesized to catalyze the activation of arylamines, known human bladder carcinogens present in cigarette smoke. The relationship between CYP1A2 phenotype and bladder cancer risk was examined in a case-control study involving 519 patients and 514 controls in Shanghai, China. Both CYP1A2 and N-acetyltransferase 2 (NAT2) phenotypic status were determined by a caffeine-based urinary...

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Source

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Identifiers

PMID: 21480221
DOI: 10.1002/ijc.26121
PMCID: PMC3167995

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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