Article
A study of linkage and association of body mass index in the Old Order Amish.
American journal of medical genetics. Part C, Seminars in medical genetics - 15 Aug 2003
Platte P, Papanicolaou G J, Johnston J, Klein C M, Doheny K F, Pugh E W, Roy-Gagnon M-H, Stunkard A J, Francomano C A, Wilson A F
Abstract excerpt
Obesity is thought to have a genetic component with the estimates of heritability ranging from 0.25-0.40. As part of an ongoing study of obesity in the Old Order Amish, seven two- and three-generation families (157 individuals) were assessed for 21 traits related to obesity, including body mass index (BMI) and BMI-percentile (a standardized distribution of BMI adjusted for age and sex). Genotyping was performed...
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