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Bivariate linkage analysis of the insulin resistance syndrome phenotypes on chromosome 7q.

Human biology - 1 Apr 2005

Lehman Donna M, Arya Rector, Blangero John, Almasy Laura, Puppala Sobha, Dyer Thomas D, Leach Robin J, O'Connell Peter, Stern Michael P, Duggirala Ravindranath

Abstract excerpt

Metabolic abnormalities of the insulin resistance syndrome (IRS) have been shown to aggregate in families and to exhibit trait-pair correlations, suggesting a common genetic component. A broad region on chromosome 7q has been implicated in several studies to contain loci that cosegregate with IRS-related traits. However, it is not clear whether such loci have any common genetic (pleiotropic) influences on the...

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PMID: 16201139
DOI: 10.1353/hub.2005.0040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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