Article
Myristoylation of endothelial cell nitric oxide synthase is important for extracellular release of nitric oxide.
Molecular and cellular biochemistry - 22 Nov 1995
Sakoda T, Hirata K, Kuroda R, Miki N, Suematsu M, Kawashima S, Yokoyama M
Abstract excerpt
Endothelial cell nitric oxide synthase (NOS) is known to have a N-myristoylation consensus sequence. Such a consensus sequence is not evident in the macrophage, smooth muscle and neuronal NOS. A functional role for this N-terminal myristoylation is not clear yet. In the present study, we examined the effect of N-terminal myristoylation on the NOS activity determined by the conversion of L-[3H]arginine to...
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