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Article

S-nitrosylation regulates nuclear translocation of chloride intracellular channel protein CLIC4.

The Journal of biological chemistry - 30 Jul 2010

Malik Mariam, Shukla Anjali, Amin Palak, Niedelman Wendy, Lee Jessica, Jividen Kasey, Phang Juanita M, Ding Jinhui, Suh Kwang S, Curmi Paul M G, Yuspa Stuart H

Abstract excerpt

Nuclear translocation of chloride intracellular channel protein CLIC4 is essential for its role in Ca(2+)-induced differentiation, stress-induced apoptosis, and modulating TGF-beta signaling in mouse epidermal keratinocytes. However, post-translational modifications on CLIC4 that govern nuclear translocation and thus these activities remain to be elucidated. The structure of CLIC4 is dependent on the redox...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20504765
DOI: 10.1074/jbc.M109.091611
PMCID: PMC2911286

Genes

CLIC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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