Article
Increased acetylcholinesterase activity in the CSF of Alzheimer patients carrying apolipoprotein epsilon4 allele.
Neuroreport - 15 Dec 1995
Soininen H, Lehtovirta M, Helisalmi S, Linnaranta K, Heinonen O, Riekkinen P
Abstract excerpt
We measured CSF acetylcholinesterase (AChE) activity in 57 Alzheimer's disease (AD) patients with different apolipoprotein E (apoE) genotypes at the early stage of the disease, and in 11 non-demented controls. The AChE activities of the whole AD group did not differ from those of controls. Howeve...
Topics
- Acetylcholinesterase
- Age of Onset
- Aged
- Alleles
- Alzheimer Disease
- Analysis of Variance
- Apolipoproteins E
- Female
- Humans
- Male
- Middle Aged
