Article
DNA-based rhesus typing: simultaneous determination of RHC and RHD status using the polymerase chain reaction.
Vox sanguinis - 1 Jan 1996
Poulter M, Kemp T J, Carritt B
Abstract excerpt
We describe a PCR-based method of performing RHD and C/c typing in a single reaction. The method is based on an earlier observation of a polymorphism in intron 2 of both genes which, in addition to detecting the RHD deletion responsible for most known D-negative phenotypes, is also associated with C/c serological type. Using this assay, we typed 105 unrelated individuals from at least four different population...
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