Article
The use of free DNA for fetal RHD genotyping in the Rh negative pregnant patient-the time has come.
American journal of obstetrics and gynecology - 1 Feb 2025
Moise Kenneth J
Abstract excerpt
Cell-free DNA to determine the fetal RHD genotype from the maternal circulation was first described in 1993. High throughput assays using polymerase chain reaction technology were introduced in Europe and gained widespread acceptance in the management of the Rhesus alloimmunized pregnancy. The specificity and sensitivity of these assays approached 99%. As confidence was gained with these results, Scandinavian...
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