Article
Rapid molecular determination of fetal rhesus E type.
Prenatal diagnosis - 1 Jun 1996
Geifman-Holtzman O, Bernstein I M, Berry S M, Bianchi D W, Holtzman E J
Abstract excerpt
The successful prophylaxis of RhD disease has brought attention to other Rh antigens, such as RhE antigen, that can cause hydrops fetalis. Our purpose was to develop simple molecular techniques to permit fetal RhE genotyping. We obtained amniotic fluid, villi, and fetal blood from two RhE-sensitized pregnancies, performed the Polymerase Chain Reaction (PCR), and made a presumptive fetal genotype diagnosis. The...
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