Article
R353Q polymorphism in the factor VII gene and cardiovascular risk in Heterozygous Familial Hypercholesterolemia: a case-control study.
Lipids in health and disease - 9 Apr 2011
Criado-García Juan, Fuentes Francisco, Cruz-Teno Cristina, García-Rios Antonio, Jiménez-Morales Anabel, Delgado-Lista Javier, Mata Pedro, Alonso Rodrigo, López-Miranda José, Pérez-Jiménez Francisco
Abstract excerpt
BACKGROUND: Heterozygous Familial Hypercholesterolemia (FH) is a genetic disorder characterized by a high risk of cardiovascular disease. Certain polymorphisms of the factor VII gene have been associated with the development of coronary artery disease and there is a known association between factor VII levels and polymorphic variants in this gene. To date, no study has evaluated the association between factor VII...
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