Debrisoquine 4-hydroxylation and sulphamethazine N-acetylation in patients with schizophrenia and major depression.

doi:10.1046/j.1365-2125.1996.33513.x

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Article

Debrisoquine 4-hydroxylation and sulphamethazine N-acetylation in patients with schizophrenia and major depression.

British journal of clinical pharmacology - 1 May 1996

Hadasová E, Franke G, Zschiesche M, Cesková E, Zelenková O, Siegmund W

Abstract excerpt

Debrisoquine 4-hydroxylation and sulphamethazine N-acetylation phenotypes were determined in 115 Czech drug-free in-patients with schizophrenia (n = 64) or major depressive disorder (n = 51). These data were compared with a control group of 321 healthy volunteers from the North-East German area o...

Topics

Acetylation
Adolescent
Adult
Aged
Cytochrome P-450 CYP2D6
Cytochrome P-450 Enzyme System
Czech Republic
Depressive Disorder
Female
Germany
Humans
Hydroxylation
Male
Middle Aged
Mixed Function Oxygenases
Phenotype
Schizophrenia
Sulfamethazine

Source

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Identifiers

PMID: 8735687
DOI: 10.1046/j.1365-2125.1996.33513.x
PMCID: PMC2042602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8735687-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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