[Genetic polymorphism in Gilbert-Meulengracht syndrome (GMS)].

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Article

[Genetic polymorphism in Gilbert-Meulengracht syndrome (GMS)].

Zeitschrift fur Gastroenterologie - 1 Feb 1993

Fengler J D, Baumgarten R, Eike E, Eike O, Siegmund W, Franke G, Zschiesche M

Abstract excerpt

N-Acetylation and debrisoquine hydroxylation phenotypes were determined in 54 patients with Gilbert's syndrome and in 247 (sulfamethazine) and 76 (debrisoquine) non-related healthy volunteers, respectively. 40 (74.1%) of the patients and 135 (54.7%) of healthy volunteers were slow acetylators (ch...

Topics

Acetylation
Arylamine N-Acetyltransferase
Cytochrome P-450 CYP2D6
Cytochrome P-450 Enzyme System
Debrisoquin
Gilbert Disease
Humans
Hydroxylation
Metabolic Clearance Rate
Mixed Function Oxygenases
Phenotype
Polymorphism, Genetic
Sulfamethazine

Source

Open in PubMed

Identifiers

PMID: 7483725

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7483725-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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