Article
[Genetic polymorphism in Gilbert-Meulengracht syndrome (GMS)].
Zeitschrift fur Gastroenterologie - 1 Feb 1993
Fengler J D, Baumgarten R, Eike E, Eike O, Siegmund W, Franke G, Zschiesche M
Abstract excerpt
N-Acetylation and debrisoquine hydroxylation phenotypes were determined in 54 patients with Gilbert's syndrome and in 247 (sulfamethazine) and 76 (debrisoquine) non-related healthy volunteers, respectively. 40 (74.1%) of the patients and 135 (54.7%) of healthy volunteers were slow acetylators (chi 2 = 6.87). In patients, the cumulative urinary excretion (CUE) of sulfamethazine (0-6 hours) was significantly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
