Nerve growth factor gene locus explains elevated renal nerve growth factor mRNA in young spontaneously hypertensive rats.

doi:10.1161/01.hyp.32.4.705

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Article

Nerve growth factor gene locus explains elevated renal nerve growth factor mRNA in young spontaneously hypertensive rats.

Hypertension (Dallas, Tex. : 1979) - 1 Oct 1998

Charchar F J, Kapuscinski M K, Harrap S B

Abstract excerpt

Nerve growth factor (NGF) controls the growth of sympathetic nerves and is increased in young spontaneously hypertensive rats (SHR). The NGF gene has been linked genetically with hypertension in the SHR strain and may explain high NGF mRNA levels. To test for genetic linkage between the NGF gene...

Topics

Animals
Blood Pressure
Gene Expression Regulation
Genotype
Kidney
Male
Nerve Growth Factors
RNA, Messenger
Rats
Rats, Inbred SHR
Rats, Inbred Strains
Species Specificity
Sympathetic Nervous System

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