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Article

Selective enhancement of antagonist ligand binding at muscarinic M2 receptors by heparin due to receptor uncoupling.

European journal of pharmacology - 18 Jan 1996

Wang S Z, Edmundson R, Zhu S Z, el-Fakahany E E

Abstract excerpt

The selectivity of heparin in inducing potentiation of binding of antagonist ligands to muscarinic receptors was investigated at the five known subtypes of muscarinic receptors. The effects of heparin on binding of [3H]N-methylscopolamine at equilibrium was studied in Chinese hamster ovary (CHO) cells which express each of the individual muscarinic receptor subtypes and in membranes prepared from these cells....

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Identifiers

PMID: 8720484
DOI: 10.1016/0014-2999(95)00674-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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