Article
Absence of mutations in the ATM gene in breast cancer patients with severe responses to radiotherapy.
British journal of cancer - 1 Jan 1997
Appleby J M, Barber J B, Levine E, Varley J M, Taylor A M, Stankovic T, Heighway J, Warren C, Scott D
Abstract excerpt
The effectiveness of cancer radiotherapy is compromised by the small proportion (approximately 5%) of patients who sustain severe normal tissue damage after standard radiotherapy treatments. Predictive tests are required to identify these highly radiosensitive cases. Patients with the rare, reces...
Topics
- Ataxia Telangiectasia Mutated Proteins
- Breast Neoplasms
- Cell Cycle Proteins
- DNA-Binding Proteins
- Female
- Humans
- Mutation
- Protein Serine-Threonine Kinases
- Proteins
- Tumor Suppressor Proteins