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Article

Role of co-regulators in metabolic and transcriptional actions of thyroid hormone.

Journal of molecular endocrinology - 1 Apr 2016

Astapova Inna

Abstract excerpt

Thyroid hormone (TH) controls a wide range of physiological processes through TH receptor (TR) isoforms. Classically, TRs are proposed to function as tri-iodothyronine (T3)-dependent transcription factors: on positively regulated target genes, unliganded TRs mediate transcriptional repression through recruitment of co-repressor complexes, while T3 binding leads to dismissal of co-repressors and recruitment of...

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Share to Co-Repressor Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Thyroid Hormone

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Source

Identifiers

PMID: 26673411
DOI: 10.1530/JME-15-0246

Genes

NCOR1
NCOR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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