Article
Involvement of the mutated M protein in altered budding polarity of a pantropic mutant, F1-R, of Sendai virus.
Journal of virology - 1 Sept 1996
Tashiro M, McQueen N L, Seto J T, Klenk H D, Rott R
Abstract excerpt
Wild-type Sendai virus buds at the apical plasma membrane domain of polarized epithelial MDCK cells, whereas a pantropic mutant, F1-R, buds at both the apical and basolateral domains. In F1-R-infected cells, polarized protein transport and the microtubule network are impaired. It has been suggest...
Topics
- Animals
- Antibodies
- Antibodies, Monoclonal
- Cell Division
- Cell Line
- Cell Membrane
- Chick Embryo
- Dogs
- Epithelium
- Mice
- Microtubules
- Mutation
- Nocodazole
- Parainfluenza Virus 1, Human
- Rabbits
- Viral Matrix Proteins
- Zinc