Possible involvement of microtubule disruption in bipolar budding of a Sendai virus mutant, F1-R, in epithelial MDCK cells.

doi:10.1128/JVI.67.10.5902-5910.1993

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Article

Possible involvement of microtubule disruption in bipolar budding of a Sendai virus mutant, F1-R, in epithelial MDCK cells.

Journal of virology - 1 Oct 1993

Tashiro M, Seto J T, Klenk H D, Rott R

Abstract excerpt

Envelope glycoproteins F and HN of wild-type Sendai virus are transported to the apical plasma membrane domain of polarized epithelial MDCK cells, where budding of progeny virus occurs. On the other hand, a pantropic mutant, F1-R, buds bipolarly at both the apical and basolateral domains, and the...

Topics

Animals
Cell Line
Chick Embryo
Colchicine
Dogs
Glycoproteins
HN Protein
Kidney
Kinetics
Methionine
Microtubules
Mutation
Nocodazole
Parainfluenza Virus 1, Human
Sulfur Radioisotopes
Tubulin
Viral Proteins

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