Article
The viral spike protein is not involved in the polarized sorting of coronaviruses in epithelial cells.
Journal of virology - 1 Jan 1998
Rossen J W, de Beer R, Godeke G J, Raamsman M J, Horzinek M C, Vennema H, Rottier P J
Abstract excerpt
Coronaviruses are assembled by budding into a pre-Golgi compartment from which they are transported along the secretory pathway to leave the cell. In cultured epithelial cells, they are released in a polarized fashion; depending on the virus and cell type, they are sorted preferentially either to...
Topics
- Animals
- Base Sequence
- Cell Line
- Cell Polarity
- Coronavirus
- DNA Primers
- Dogs
- Epithelial Cells
- LLC-PK1 Cells
- Membrane Glycoproteins
- Mice
- Murine hepatitis virus
- Mutation
- Spike Glycoprotein, Coronavirus
- Swine
- Temperature
- Transmissible gastroenteritis virus
- Tunicamycin