Article
The viral spike protein is not involved in the polarized sorting of coronaviruses in epithelial cells.
Journal of virology - 1 Jan 1998
Rossen J W, de Beer R, Godeke G J, Raamsman M J, Horzinek M C, Vennema H, Rottier P J
Abstract excerpt
Coronaviruses are assembled by budding into a pre-Golgi compartment from which they are transported along the secretory pathway to leave the cell. In cultured epithelial cells, they are released in a polarized fashion; depending on the virus and cell type, they are sorted preferentially either to the apical domain or to the basolateral plasma membrane domain. In this study, we investigated the role of the...
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