Activity of vesicular stomatitis virus M protein mutants in cell rounding is correlated with the ability to inhibit host gene expression and is not correlated with virus assembly function.

doi:10.1006/viro.1996.8415

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Article

Activity of vesicular stomatitis virus M protein mutants in cell rounding is correlated with the ability to inhibit host gene expression and is not correlated with virus assembly function.

Virology - 3 Mar 1997

Lyles D S, McKenzie M O

Abstract excerpt

In addition to its role in virus assembly, the matrix (M) protein of vesicular stomatitis virus (VSV) is involved in virus-induced cell rounding and inhibition of host-directed gene expression. Previous experiments have shown that two M protein mutants genetically dissociate the ability of M prot...

Topics

Animals
Cell Line
Cricetinae
Cytoskeleton
Gene Expression Regulation, Viral
Mutation
RNA, Messenger
Transfection
Vesicular stomatitis Indiana virus
Viral Matrix Proteins
Virus Assembly

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