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Article

Reverse genetics studies on the filamentous morphology of influenza A virus.

The Journal of general virology - 1 Mar 2003

Bourmakina Svetlana V, García-Sastre Adolfo

Abstract excerpt

We have investigated the genetic determinants responsible for the filamentous morphology of influenza A viruses, a property characteristic of primary virus isolates. A plasmid-based reverse genetics system was used to transfer the M segment of influenza A/Udorn/72 (H3N2) virus into influenza A/WSN/33 (H1N1) virus. While WSN virions display spherical morphology, recombinant WSN-Mud virus acquired the ability of...

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PMID: 12604801
DOI: 10.1099/vir.0.18803-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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