Article
Altered budding site of a pantropic mutant of Sendai virus, F1-R, in polarized epithelial cells.
Journal of virology - 1 Oct 1990
Tashiro M, Yamakawa M, Tobita K, Seto J T, Klenk H D, Rott R
Abstract excerpt
A protease activation mutant of Sendai virus, F1-R, causes a systemic infection in mice, whereas wild-type virus is exclusively pneumotropic (M. Tashiro, E. Pritzer, M. A. Khoshnan, M. Yamakawa, K. Kuroda, H.-D. Klenk, R. Rott, and J. T. Seto, Virology 165:577-583, 1988). Budding of F1-R has been observed bidirectionally at the apical and basolateral surfaces of the bronchial epithelium of mice and of MDCK cells,...
Topics
- Animals
- Antigens, Viral
- Cell Line
- Cell Transformation, Viral
- Chick Embryo
- Glycoproteins
- Kinetics
- Methionine
- Mutation
- Parainfluenza Virus 1, Human
- Viral Proteins
