Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic change in actinic keratoses.

Oncogene - 20 Jun 1996

Rehman I, Takata M, Wu Y Y, Rees J L

Abstract excerpt

Actinic keratoses (AKs) are small scaly red areas of skin characterised histologically by dysplasia, a minority of which are thought to be precursors of squamous cell carcinoma (SCC), and which show a high frequency of regression. Surprisingly, in view of their benign clinical course, they show a high frequency of loss of heterozygosity (LOH) with a median loss of four loci with almost 20% of lesions showing loss...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to Cell Division

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosome Deletion

Share to Genes, p53

Share to Heterozygote

Share to Molecular Sequence Data

Share to Nuclear Proteins

Source

Identifiers

PMID: 8700506

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic change in actinic keratoses.PMID 8700506Read ↗

High frequency of loss of heterozygosity in actinic keratoses, a usually benign disease.Semantic proximity Read ↗

Genomic instability, mutations and expression analysis of the tumour suppressor genes p14(ARF), p15(INK4b), p16(INK4a) and p53 in actinic keratosis.Semantic proximity Read ↗

The Genomic Landscape of Actinic Keratosis.Semantic proximity Read ↗

Genomic Progression of Precancerous Actinic Keratosis to Squamous Cell Carcinoma.Semantic proximity Read ↗

P53 staining index and zonal staining patterns in actinic keratoses.Semantic proximity Read ↗

BRAF and RKIP are significantly decreased in cutaneous squamous cell carcinoma.Semantic proximity Read ↗

Gene Expression Patterns of Normal Human Skin, Actinic Keratosis, and Squamous Cell CarcinomaSemantic proximity Read ↗

[Actinic keratoses].Semantic proximity Read ↗

p53 mutations are common and early events that precede tumor invasion in squamous cell neoplasia of the skin.Semantic proximity Read ↗

Lip cancer and pre-cancerous lesions harbor TP53 mutations, exhibit allelic loss at 9p, 9q, and 17p, but no BRAFV600E mutations.Semantic proximity Read ↗

Emergence and Evolution of Mutational Hotspots in Sun-Damaged Skin.Semantic proximity Read ↗

<i>MYC</i>gene numerical aberrations in actinic keratosis and cutaneous squamous cell carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.