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Article

<i>MYC</i>gene numerical aberrations in actinic keratosis and cutaneous squamous cell carcinoma

11 Jun 2009

Abstract excerpt

BACKGROUND: The genetic alterations that drive the transition from actinic keratoses (AKs) to cutaneous squamous cell carcinomas (SCCs) have not been defined precisely. Amplification and/or overexpression of the MYC proto-oncogene have been demonstrated in several human, malignant tumours including head and neck SCCs. OBJECTIVES: To evaluate the presence of MYC genomic aberrations in both AKs and SCCs. METHODS:...

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Share to Cutaneous Melanoma Detection and Management
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PMID: 19673870
DOI: 10.1111/j.1365-2133.2009.09351.x

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