Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The urease enzyme of Helicobacter pylori does not function as an adhesin.

Infection and immunity - 1 Jul 1996

Clyne M, Drumm B

Abstract excerpt

Helicobacter pylori urease is essential for colonization of the gastric mucosa irrespective of whether the stomach is acidic or hypochlorhydric. It has therefore been speculated that the enzyme functions as an adhesin. The aim of this study was to compare the adherence of H. pylori N6 with the adherence of an isogenic urease-negative mutant, strain N6(ureB::TnKm), to gastric cells. Strain N6 originated from a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adhesins, Bacterial
Share to Bacterial Adhesion
Share to Cell Line

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cells, Cultured

Share to Genes, Bacterial

Share to Helicobacter pylori

Share to Mutation

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 8698515
DOI: 10.1128/iai.64.7.2817-2820.1996
PMCID: PMC174146

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The urease enzyme of Helicobacter pylori does not function as an adhesin.PMID 8698515Read ↗

Surface properties of Helicobacter pylori urease complex are essential for persistence.Semantic proximity Read ↗

Essential role of urease in vitro and in vivo Helicobacter pylori colonization study using a wild-type and isogenic urease mutant strain.Semantic proximity Read ↗

Helicobacter pylori urease activity is influenced by ferric uptake regulator.Semantic proximity Read ↗

Helicobacter pylori adherence to gastric epithelial cells: a role for non-adhesin virulence genes.Semantic proximity Read ↗

Helicobacter pylori requires an acidic environment to survive in the presence of urea.Semantic proximity Read ↗

Characterization of Helicobacter pylori urease mutants.Semantic proximity Read ↗

Helicobacter pylori urease binds to class II MHC on gastric epithelial cells and induces their apoptosis.Semantic proximity Read ↗

Role of urease in megasome formation and Helicobacter pylori survival in macrophages.Semantic proximity Read ↗

Construction of isogenic urease-negative mutants of Helicobacter pylori by allelic exchange.Semantic proximity Read ↗

A Novel Assay for Easy and Rapid Quantification of Helicobacter pylori Adhesion.Semantic proximity Read ↗

Factors affecting growth and antibiotic susceptibility of Helicobacter pylori: effect of pH and urea on the survival of a wild-type strain and a urease-deficient mutant.Semantic proximity Read ↗

Dependence of Helicobacter pylori urease activity on the nickel-sequestering ability of the UreE accessory protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.