Article
Characterization of Helicobacter pylori urease mutants.
Infection and immunity - 1 May 1992
Segal E D, Shon J, Tompkins L S
Abstract excerpt
The association between Helicobacter pylori, gastritis, and peptic ulcer is well established, and the association of infection with gastric cancer has been noted in several developing countries. However, the pathogenic mechanism(s) leading to disease states has not been elucidated. The H. pylori urease is thought to be a determinant of pathogenicity, since the enzyme is produced by all H. pylori clinical...
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