Article
Essential role of urease in vitro and in vivo Helicobacter pylori colonization study using a wild-type and isogenic urease mutant strain.
Journal of clinical gastroenterology - 1 Jan 1995
Karita M, Tsuda M, Nakazawa T
Abstract excerpt
To determine the role of urease in colonization of Helicobacter pylori, we constructed a Ure- mutant by allelic exchange mutagenesis and examined the characteristics of the Ure- mutant and its parental strain. We also evaluated whether both strains would be able to colonize the stomach of nude mi...
Topics
- Alleles
- Animals
- Blotting, Southern
- Helicobacter Infections
- Helicobacter pylori
- Male
- Mice
- Mice, Inbred BALB C
- Mutagenesis
- Phenotype
- Urease
