Article
Induction of multilocus mutations at the Tk1 locus after X irradiation of L5178Y cells at different times in the mitotic cycle.
Radiation research - 1 Aug 1996
Evans H H, Mencl J, Ricanati M, Horng M F, Chaudhry M A, Jiang Q, Hozier J, Liechty M
Abstract excerpt
TK1+/- L5178Y-R16 cells were separated into G1, S and G2/M-phase populations by centrifugal elutriation and were treated with 1.5 Gy X radiation. Cells irradiated in the G1 and G2/M phases were most sensitive to the cytotoxic effects of radiation, while cells irradiated in the G2/M phase showed t...
Topics
- Animals
- Base Sequence
- Cell Cycle
- Cell Survival
- Chromosome Deletion
- Chromosome Mapping
- Galactokinase
- Leukemia L5178
- Mice
- Mitosis
- Molecular Sequence Data
- Mutation
- Thymidine Kinase
- Tumor Cells, Cultured
- X-Rays
