Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fluorescent PCR: a new technique for PGD of sex and single-gene defects.

Journal of assisted reproduction and genetics - 1 Feb 1996

Findlay I, Quirke P, Hall J, Rutherford A

Abstract excerpt

BACKGROUND: For single-cell diagnosis, particularly preimplantation genetic diagnosis to be successful four main criteria must be achieved: sensitivity, reliability, accuracy, and identification/elimination of contamination. METHODS AND RESULTS: Fluorescent PCR achieves all four necessary criteria and, in addition, currently allows genes on up to nine chromosomes to be simultaneously investigated. Fluorescent PCR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cystic Fibrosis
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Fingerprinting

Share to DNA Mutational Analysis

Share to DNA Primers

Share to Genetic Markers

Share to Heterozygote

Source

Identifiers

PMID: 8688597
DOI: 10.1007/BF02072528

Genes

PGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fluorescent PCR: a new technique for PGD of sex and single-gene defects.PMID 8688597Read ↗

Strategies for preimplantation genetic diagnosis of single gene disorders by DNA amplificationSemantic proximity Read ↗

Multiple genetic diagnoses from single cells using multiplex PCR: reliability and allele dropout.Semantic proximity Read ↗

Allelic drop-out and preferential amplification in single cells and human blastomeres: implications for preimplantation diagnosis of sex and cystic fibrosis.Semantic proximity Read ↗

Single cell polymerase chain reaction for preimplantation genetic diagnosis: methods, strategies, and limitations.Semantic proximity Read ↗

Assessment of diagnostic quantitative fluorescent multiplex polymerase chain reaction assays performed on single cells.Semantic proximity Read ↗

DNA fingerprinting of sister blastomeres from human IVF embryos.Semantic proximity Read ↗

Preimplantation genetic diagnosis for single gene disorders: experience with five single gene disorders.Semantic proximity Read ↗

Preimplantation genetic diagnosis: current status and new developments.Semantic proximity Read ↗

Allele dropout in polar bodies and blastomeres.Semantic proximity Read ↗

[First attempts in preimplantation genetic diagnosis: genetic analysis].Semantic proximity Read ↗

Single-cell high resolution melting analysis: A novel, generic, pre-implantation genetic diagnosis (PGD) method applied to cystic fibrosis (HRMA CF-PGD).Semantic proximity Read ↗

PCR analysis of DNA sequences in single cells: single sperm gene mapping and genetic disease diagnosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.