Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA fingerprinting of sister blastomeres from human IVF embryos.

Human reproduction (Oxford, England) - 1 Mar 2002

Katz Mandy G, Trounson A O, Cram D S

Abstract excerpt

BACKGROUND: Previously published single cell DNA fingerprinting systems have been plagued by high rates of allele drop-out (ADO) and preferential amplification (PA) preventing clinical application in preimplantation genetic diagnosis. METHODS: Tetranucleotide microsatellite markers with high heterozygosity, known allelic size ranges and minimal PCR stutter artefacts were selected for chromosomes X, 13, 18 and 21...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blastomeres
Share to DNA Fingerprinting
Share to Down Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Mammalian

Share to Fertilization in Vitro

Share to Fluorescence

Share to Gene Amplification

Share to Single-Blind Method

Source

Identifiers

PMID: 11870131
DOI: 10.1093/humrep/17.3.752

Genes

ADO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA fingerprinting of sister blastomeres from human IVF embryos.PMID 11870131Read ↗

Fluorescent PCR: a new technique for PGD of sex and single-gene defects.Semantic proximity Read ↗

Strategies for preimplantation genetic diagnosis of single gene disorders by DNA amplificationSemantic proximity Read ↗

Identification of microsatellite markers <1 Mb from the FMR1 CGG repeat and development of a single-tube tetradecaplex PCR panel of highly polymorphic markers for preimplantation genetic diagnosis of fragile X syndrome.Semantic proximity Read ↗

Reliable gender screening for human preimplantation embryos, using multiple DNA target-sequencesSemantic proximity Read ↗

Mutation and haplotype analysis for Duchenne muscular dystrophy by single cell multiple displacement amplification.Semantic proximity Read ↗

Allelic drop-out and preferential amplification in single cells and human blastomeres: implications for preimplantation diagnosis of sex and cystic fibrosis.Semantic proximity Read ↗

Single-tube tetradecaplex panel of highly polymorphic microsatellite markers < 1 Mb from F8 for simplified preimplantation genetic diagnosis of hemophilia A.Semantic proximity Read ↗

Preimplantation single-cell analysis of multiple genetic loci by whole-genome amplification.Semantic proximity Read ↗

Detailed investigation of factors influencing amplification efficiency and allele drop-out in single cell PCR: implications for preimplantation genetic diagnosis.Semantic proximity Read ↗

A novel single-cell DNA fingerprinting method successfully distinguishes sibling human embryos.Semantic proximity Read ↗

The clinical application of single-sperm-based SNP haplotyping for PGD of osteogenesis imperfectaSemantic proximity Read ↗

Accuracy of preimplantation diagnosis of single-gene disorders by polar body analysis of oocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.