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Article

The potential use of rifabutin for treatment of patients diagnosed with rifampicin-resistant tuberculosis.

The Journal of antimicrobial chemotherapy - 1 Oct 2018

Whitfield Michael G, Warren Robin M, Mathys Vanessa, Scott Lesley, De Vos Elise, Stevens Wendy, Streicher Elizabeth M, Groenen Guido, Sirgel Frederick A, Van Rie Annelies

Abstract excerpt

Background: Use of the Xpert MTB/RIF assay has increased the number of people diagnosed with rifampicin-resistant tuberculosis (RR-TB), especially in South Africa where Xpert is now the initial diagnostic for individuals with TB symptoms. We hypothesized that a proportion of RR-TB patients determined by Xpert can be treated with a rifabutin-containing regimen. Methods: Rifabutin susceptibility by rpoB mutation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29982641
DOI: 10.1093/jac/dky248
PMCID: PMC6148329

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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