Ongoing immunoglobulin gene mutations in mantle cell lymphomas.

doi:10.1046/j.1365-2141.1997.8712503.x

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Article

Ongoing immunoglobulin gene mutations in mantle cell lymphomas.

British journal of haematology - 1 Jan 1997

Du M Q, Diss T C, Xu C F, Wotherspoon A C, Isaacson P G, Pan L X

Abstract excerpt

Mantle cell lymphomas (MCL) frequently show a vaguely follicular growth pattern. This phenomenon is thought to result from the colonization of reactive B-cell follicles by tumour cells. In view of the unique property of the germinal centre environment, antigen stimulation may play a role in the e...

Topics

Base Sequence
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 14
Gene Rearrangement, B-Lymphocyte, Heavy Chain
Genes, Immunoglobulin
Humans
Immunoglobulin Heavy Chains
Lymphoma, Non-Hodgkin
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Translocation, Genetic

Source

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Identifiers

PMID: 9012698
DOI: 10.1046/j.1365-2141.1997.8712503.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9012698-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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