Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ongoing Ig gene hypermutation in salivary gland mucosa-associated lymphoid tissue-type lymphomas.

Blood - 1 May 1997

Bahler D W, Miklos J A, Swerdlow S H

Abstract excerpt

Salivary gland mucosa-associated lymphoid tissue (MALT) type lymphomas are typically indolent B-cell neoplasms that are often associated with Sjogren's syndrome. To better define the cell of origin and evaluate whether antigen receptor stimulation may be playing a role in tumor growth, the Ig hea...

Topics

Amino Acid Sequence
Base Sequence
DNA Mutational Analysis
DNA Primers
Gene Rearrangement
Genes, Immunoglobulin
Genetic Variation
Humans
Immunoglobulin Heavy Chains
Immunoglobulin Light Chains
Immunoglobulin Variable Region
Lymphoma, B-Cell, Marginal Zone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Point Mutation

Polymerase Chain Reaction

Salivary Gland Neoplasms

Sjogren's Syndrome

Source

Identifiers

PMID: 9129040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9129040-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ongoing Ig gene hypermutation in salivary gland mucosa-associated lymphoid tissue-type lymphomas.PMID 9129040Read ↗

Salivary gland mucosa-associated lymphoid tissue lymphoma immunoglobulin VH genes show frequent use of V1-69 with distinctive CDR3 featuresSemantic proximity Read ↗

Somatic hypermutation in low-grade mucosa-associated lymphoid tissue- type B-cell lymphomaSemantic proximity Read ↗

Immunoglobulin VH genes of high-grade mucosa-associated lymphoid tissue lymphomas show a high load of somatic mutations and evidence of antigen-dependent affinity maturation.Semantic proximity Read ↗

VH and VL gene analysis in sporadic Burkitt's lymphoma shows somatic hypermutation, intraclonal heterogeneity, and a role for antigen selection.Semantic proximity Read ↗

Ongoing mutation in MALT lymphoma immunoglobulin gene suggests that antigen stimulation plays a role in the clonal expansion.Semantic proximity Read ↗

Intraclonal offspring expansion of gastric low-grade MALT-type lymphoma: evidence for the role of antigen-driven high-affinity mutation in lymphomagenesis.Semantic proximity Read ↗

Somatic hypermutation of immunoglobulin heavy chain variable region genes in thymic marginal zone B-cell lymphoma of MALT type of a patient with Sjögren's syndrome.Semantic proximity Read ↗

Use of similar immunoglobulin VH gene segments by MALT lymphomas of the ocular adnexa.Semantic proximity Read ↗

Clonal Salivary Gland Infiltrates Associated With Myoepithelial Sialadenitis (Sjogren's Syndrome) Begin as Nonmalignant Antigen-Selected ExpansionsSemantic proximity Read ↗

Characterization of genetic events involving IgH switch regions in gastric low-grade MALT lymphomas and B-CLLSemantic proximity Read ↗

Ongoing immunoglobulin gene mutations in mantle cell lymphomas.Semantic proximity Read ↗

Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.