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Article

Epitope-based therapeutic targets in HCV genotype 1 non-structural proteins: a novel strategy to combat emerging drug resistance.

Frontiers in cellular and infection microbiology - 1 Jan 2024

Tudi Mireayi, Sawuti Adili, Abudurusuli Maimaitituerhong, Wu Chao, Chen Xiaoyu, Ailimu Gulimire, Wulayin Kuerbannisa, Tuerxun Maimaitiaili

Abstract excerpt

Introduction: The hepatitis C virus (HCV) poses a major global health challenge, with its non-structural proteins being essential for viral replication and pathogenesis. Mutations in these proteins significantly contribute to drug resistance, necessitating innovative therapeutic strategies. This study aims to identify epitope-based therapeutic targets in the non-structural proteins of HCV genotype 1, employing...

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Share to Antiviral Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Molecular Docking Simulation

Share to T-Lymphocytes, Cytotoxic

Share to Viral Nonstructural Proteins

Source

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Identifiers

PMID: 39575309
DOI: 10.3389/fcimb.2024.1480987
PMCID: PMC11578958

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