Article
Temporal relationship between elongation of the HIV type 1 glycoprotein 120 V2 domain and the conversion toward a syncytium-inducing phenotype.
AIDS research and human retroviruses - 1 Dec 1995
Fouchier R A, Broersen S M, Brouwer M, Tersmette M, Van't Wout A B, Groenink M, Schuitemaker H
Abstract excerpt
The second and third variable domains (V2 and V3) of the human immunodeficiency virus type 1 (HIV-1) gp120 envelope molecule have been shown to be determinants of syncytium-inducing (SI) capacity. Previously we have reported evidence that increased length of the V2 domain and duplication or reloc...
Topics
- Amino Acid Sequence
- Base Sequence
- Biomarkers
- Giant Cells
- HIV Envelope Protein gp120
- HIV-1
- Humans
- Molecular Sequence Data
- Peptide Chain Elongation, Translational
- Phenotype
- Polymerase Chain Reaction
- Sensitivity and Specificity
- Time Factors