Article
Emergence of syncytium-inducing human immunodeficiency virus type 1 variants coincides with a transient increase in viral RNA level and is an independent predictor for progression to AIDS.
The Journal of infectious diseases - 1 Aug 1998
Spijkerman I, de Wolf F, Langendam M, Schuitemaker H, Coutinho R
Abstract excerpt
To study the dynamics of human immunodeficiency virus (HIV)-1 RNA level around the time of conversion from non-syncytium-inducing (NSI) to syncytium-inducing (SI) phenotype and to study the predictive value of the SI phenotype for progression to AIDS, sequential samples from 123 HIV-infected homo...
Topics
- Acquired Immunodeficiency Syndrome
- Disease Progression
- Genetic Variation
- Giant Cells
- HIV Seropositivity
- HIV-1
- Homosexuality, Male
- Humans
- Male
- Phenotype
- Predictive Value of Tests
- RNA, Viral
- Viral Load