Article
Conversion rate towards a syncytium-inducing (SI) phenotype during different stages of human immunodeficiency virus type 1 infection and prognostic value of SI phenotype for survival after AIDS diagnosis.
The Journal of infectious diseases - 1 Jan 1999
Koot M, van Leeuwen R, de Goede R E, Keet I P, Danner S, Eeftinck Schattenkerk J K, Reiss P, Tersmette M, Lange J M, Schuitemaker H
Abstract excerpt
The presence of syncytium-inducing (SI) human immunodeficiency virus type 1 (HIV-1) variants is predictive for accelerated progression to AIDS. This study showed that a 4-year survival with AIDS also occurred significantly more often for patients who lacked SI variants. However, multivariate Cox...
Topics
- Acquired Immunodeficiency Syndrome
- CD4 Lymphocyte Count
- Cytopathogenic Effect, Viral
- Genetic Variation
- HIV Infections
- HIV-1
- Humans
- Netherlands
- Phenotype
- Prognosis
- Proportional Hazards Models
- Survival Rate