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Article

Genotypic analysis of respiratory mucous sulfation defects in cystic fibrosis.

The Journal of clinical investigation - 1 Dec 1995

Zhang Y, Doranz B, Yankaskas J R, Engelhardt J F

Abstract excerpt

Intracellular dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) has been proposed to alter endosomal acidification. The most widely studied consequence of this defect has been alterations in the biochemical properties of cystic fibrosis (CF) respiratory mucus glycoproteins. However, studies confirming the existence of mucous processing defects in CF have been hindered by the lack of in...

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Identifiers

PMID: 8675672
DOI: 10.1172/JCI118372
PMCID: PMC186012

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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