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Article

Genotypic analysis of respiratory mucous sulfation defects in cystic fibrosis.

The Journal of clinical investigation - 1 Dec 1995

Zhang Y, Doranz B, Yankaskas J R, Engelhardt J F

Abstract excerpt

Intracellular dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) has been proposed to alter endosomal acidification. The most widely studied consequence of this defect has been alterations in the biochemical properties of cystic fibrosis (CF) respiratory mucus glycoprot...

Topics

Adolescent
Adult
Animals
Bronchi
Cells, Cultured
Cystic Fibrosis
Female
Glucosamine
Humans
Lung Transplantation
Male
Mice
Mice, Nude

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mucins

Mutation

Point Mutation

Radioisotope Dilution Technique

Reference Values

Source

Open in PubMed Open full text

Identifiers

PMID: 8675672
DOI: 10.1172/JCI118372
PMCID: PMC186012

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8675672-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Genotypic analysis of respiratory mucous sulfation defects in cystic fibrosis.PMID 8675672Read ↗

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