Article
Ultrastructural localization of variant forms of cystic fibrosis transmembrane conductance regulator in human bronchial epithelial of xenografts.
American journal of respiratory cell and molecular biology - 1 Jul 1994
Yang Y, Engelhardt J F, Wilson J M
Abstract excerpt
Cystic fibrosis (CF) is caused by mutations in the gene encoding a cyclic adenosine monophosphate (cAMP)-regulated chloride (CI) channel called the CF transmembrane conductance regulator (CFTR). Previous in vitro studies have indicated that the most common mutation, delta F508 CFTR (a deletion of...
Topics
- Adenoviridae
- Animals
- Bronchi
- Cell Line, Transformed
- Cells, Cultured
- Chloride Channels
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Epithelium
- Gene Transfer Techniques
- Humans