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Article

Immunochemical analysis of mutant CFTR in lung explants.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2012

van Barneveld Andrea, Zander Isabell, Hyde Rebecca, Länger Florian, Simon André, Krüger Marcus, Ballmann Manfred, Derichs Nico, Tümmler Burkhard

Abstract excerpt

BACKGROUND/AIMS: Knowledge about the abundance and distribution of CFTR protein glycoforms in native lung tissue is scarce. For upcoming studies with correctors and potentiators for CFTR it is important to get more information about mutant CFTR protein biochemistry. Target for novel treatment is the most afflicted organ in cystic fibrosis (CF), the lung. METHODS: Lung tissue sampled from patients with CF and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22832190
DOI: 10.1159/000341440

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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