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Article

Characterization of a novel SHV beta-lactamase variant that resembles the SHV-5 enzyme.

FEMS microbiology letters - 1 Jun 1996

Prinarakis E E, Tzelepi E, Gazouli M, Mentis A F, Tzouvelekis L S

Abstract excerpt

An SHV type beta-lactamase frequently found in enterobacteria isolated in Greek hospitals was analyzed. The enzyme (SHV-5a) conferred resistance to ceftazidime and aztreonam. The DNA sequence of the structural gene was determined. The deduced amino acid sequence showed that positions 70-73 were occupied by the active site tetrad Ser-Thr-Phe-Lys. As in SHV-5, Ser-238 and Lys-240 were present. However, one deletion...

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Source

Identifiers

PMID: 8674992
DOI: 10.1111/j.1574-6968.1996.tb08207.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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