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Article

Renal agenesis and hypodysplasia in ret-k- mutant mice result from defects in ureteric bud development.

Development (Cambridge, England) - 1 Jun 1996

Schuchardt A, D'Agati V, Pachnis V, Costantini F

Abstract excerpt

The c-ret gene encodes a receptor tyrosine kinase that is expressed in the Wolffian duct and ureteric bud of the developing excretory system. Newborn mice homozygous for a mutation in c-ret displayed renal agenesis or severe hypodysplasia, suggesting a critical role for this gene in metanephric k...

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PMID: 8674430
DOI: 10.1242/dev.122.6.1919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8674430-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Renal agenesis and hypodysplasia in ret-k- mutant mice result from defects in ureteric bud development.PMID 8674430Read ↗

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